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Best Practices for Prescribing and Administering Naloxone for Opioid Toxicity in Adults
Recorded for 2025 National Conference
Credit(s):
0.97 Contact Hour(s) of CE; all of which may be applied towards Pharmacology
July 15, 2026 (11:55 p.m. CT) CE for this activity will not be available after this date.
This CE activity was recorded for the 2025 AANP National Conference.
This activity includes closed captioning.
Delivery Note: The content for this activity was previously presented during the 2025 AANP National Conference. If you already completed the content of this activity while attending the live or virtual conference, you should not complete this content a second time. Learners should only complete ONE delivery-method to earn credit. Completing multiple delivery options for the same activity is considered duplicate credit for the same content and will not be accepted by regulatory bodies.
Overview The opioid epidemic has influenced opioid prescribing patterns among nurse practitioners practicing in both inpatient and outpatient settings. For some adult patients, opioids may be included as part of a multimodal approach to pain management, however healthcare literacy, comorbidities, medication interactions, medication adherence, and unintentional overdose can compromise patient safety and increase their risk for death. This presentation will review the pharmacodynamics and pharmacokinetics of both opioids and naloxone and provide nurse practitioners with updates on naloxone prescribing practices, including resources for making naloxone accessible and affordable to patients. It will emphasize safe naloxone administration practices in inpatient and outpatient environments and provide an overview of educational and community resources for patients and caregivers.
Objectives
Identify the current evidence that supports naloxone use in adults with opioid toxicity in inpatient and outpatient settings.
Review the pharmacological principles that guide naloxone dosing and reduce the adverse side-effects of naloxone use.
Appraise the strategies that can improve naloxone prescribing patterns and assist with administration best practices.
Speaker Megan Shifrin, DNP, ACNP, FAANP Disclosure This program was planned in accordance with AANP CE Standards and Policies. The speaker has the following disclosures:
I have nothing to disclose.
Disclaimer Individuals who have contributed to the CE Center (content originally from the 2025 AANP National Conference) were carefully selected for their knowledge and experience in the subject area under review. This presentation is informational only and may contain opinions of the authors from their personal experience that do not necessarily express the opinions of the American Association of Nurse Practitioners (AANP). The activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Clinical practice is a constantly changing process and new information becomes available every day. Neither AANP nor the contributing individuals can warrant that the material will continue to be accurate, nor do they warrant that the material is completely free of errors upon publication. Attendees and participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.
CE Credit Instructions
Read this activity description, including objectives and disclosures.
Complete all educational content:
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After completing all educational content, go to the Next Steps button:
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Additional Information For questions or more information concerning this online CE activity,please visit the AANP Help Center to find answers to frequently asked questions and request assistance.
0.97 Contact Hour(s) of CE, All of which may be applied towards Pharmacology
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