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Case-Based Challenges in Lipid Management: Integrating Current Evidence and Evolving Best Practices to Optimize Patient Care
Part 1: ASCVD Risk Assessment as a Foundation for Lipid Treatment | Part 2: Overcoming Statin Intolerance to Mitigate ASCVD Risk | Part 3: Maximizing Treatment Adherence and Optimizing Clinical Outcomes with Nonstatin Therapies
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Category: Primary Care, [Free CE for AANP Members], Cardiology, Cert Exam Domain - Assessment, Cert Exam Domain - Diagnosis, Cert Exam Domain - Evaluation, Cert Exam Domain - Planning, Diagnostic Tests, Individual Across the Lifespan, NP Students, Pharmacology, Preventable Disease, Women's Health (show less)
Subcategory: Assessment, Bundle, Cardiometabolic, Diagnosis, Diagnostic Tests, Dyslipidemia, Evaluation (Follow-up), Evidence-Based Guidelines, Guidelines, Health Promotion, Hypercholesterolemia, Lipids, New Medication, Outpatient, Patient-Centered, Pharmacology, Primary Care, Risk Management, Treatment, Treatment Plan
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Released: 09/24/2025
Expires: 09/30/2026 (subject to change)
- CE for this activity will not be available after this date.
 | This activity includes transcription. |
Overview
This multi-component continuing education program on lipid management equips nurse practitioners with evidence-based strategies to assess ASCVD risk, optimize lipid screening, and integrate emerging tools such as apoB, Lp(a), and coronary calcium scoring into practice. Through interactive case studies, participants explore real-world challenges including statin intolerance, nonstatin therapy options, and patient-centered approaches to treatment intensification. The program emphasizes shared decision-making, adherence strategies, and the use of novel lipid-lowering agents to improve outcomes and reduce cardiovascular risk across diverse patient populations.- Part 1: ASCVD Risk Assessment as a Foundation for Lipid Treatment - This session reviews best practices for evaluating ASCVD risk, including the role of traditional risk calculators, novel biomarkers (apoB, Lp(a)), and coronary calcium scoring, to guide individualized treatment strategies. Participants will gain practical tools to implement evidence-based lipid screening and early intervention.
- Part 2: Overcoming Statin Intolerance to Mitigate ASCVD Risk - This module explores the recognition and management of statin intolerance, strategies for safe rechallenge, and the use of nonstatin agents when LDL-C goals are not met. Emphasis is placed on balancing efficacy, safety, and patient preferences in lipid-lowering therapy.
- Part 3: Maximizing Treatment Adherence and Optimizing Clinical Outcomes with Nonstatin Therapies - Focusing on long-term management, this case-based module highlights barriers to adherence and introduces approaches such as shared decision-making, patient-centered communication, and extended-dosing nonstatin options. The session equips NPs to reduce treatment burden and improve patient outcomes.
Objectives
- Part 1:
- Describe current best practices for evaluating atherosclerotic cardiovascular disease (ASCVD) risk, with emphasis on clinically relevant risk enhancers.
- Design an evidence-driven and guideline-concordant lipid-lowering treatment plan, encompassing both lifestyle and pharmacologic interventions, based on risk level.
- Part 2:
- Examine the burden of statin insufficiency and/or statin intolerance and the consequent need for nonstatin lipid-lowering therapeutic options.
- Review best practice approaches for improving patient adherence to lipid-lowering therapies, including the adaptive utility of novel, nonstatin agents.
- Part 3:
- Review best practice approaches for improving patient adherence to lipid-lowering therapies, including the adaptive utility of novel, nonstatin agents.
- Implement patient-centric protocols for promoting treatment adherence using shared decision-making, active communication, and novel agents with less frequent dosing.
Speakers
Lynne Braun, PhD, CNP, FAHA, FAANP, FNLA, FPCNA, FAAN
Nicole Ciffone, MS, ANP-C, AACC, FNLA
Disclosure
This program was planned in accordance with AANP CE Standards and Policies.
The speakers have the following disclosures:- Dr. Lynne Braun has disclosed that she is an author for UpToDate.
- Nicole Ciffone has disclosed that she serves as a speaker consultant for Amgen, Ionis, Lilly, and Regeneron.
All Planners involved in this activity have no relevant financial relationships to disclose.
All relevant financial relationships have been mitigated.
This activity is supported by educational grant funding provided by Amgen and Novartis.
Disclaimer
Individuals who have contributed to the CE Center were carefully selected for their knowledge and experience in the subject area under review. This presentation is informational only and may contain opinions of the authors from their personal experience that do not necessarily express the opinions of the American Association of Nurse Practitioners (AANP). The activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Clinical practice is a constantly changing process and new information becomes available every day. Neither AANP nor the contributing individuals can warrant that the material will continue to be accurate, nor do they warrant that the material is completely free of errors upon publication. Attendees and participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.
CE Credit Instructions- Read this activity description, including objectives and disclosures.
- Complete the educational content.This activity is divided into three modules and each module contains a video and case study activity. Learners can complete any or all modules based on their interest. For each module:
- Click on the Video activity block.
- Complete the Pretest associated to the activity.
- Click the Play button to watch the activity presentation. Full participation credit for the activity will be received once the entire video has been watched.
- Click on the Additional Resources button to review all additional materials provided (handouts, post-test reviews, any other downloadable resources).
- After completing all content, click on the blue Next Steps button followed by the Get Certificate button. This will show a brief confirmation of completion message for this part of the activity and direct learners to continue to the Case Study portion.
- Click on the Interactive Case Study activity block.
- Click the Play button to launch the interactive case studies module. This activity will open in a new window. Complete all parts of the interactive case study module and close the window to return to your CE Activities list. We recommend using the "Exit Course" button shown on the final page of the interactive case study module.
- Click the Next Steps button. This will show a brief confirmation of completion message for this part of the activity and direct learners to continue to the post-test and evaluation.
- Click on the next activity block.
- Click on the Next Steps button.
- Complete the post-test for the module.
- Complete and submit the evaluation for the activity to receive continuing education credit for that module.
Additional Information
For questions or more information concerning this online CE activity, please visit the AANP Help Center to find answers to frequently asked questions and request assistance.
2.68 Contact Hour(s) of CE,
1.45 of which may be applied towards Pharmacology
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