Obesity: Where Pathophysiology and NP Primary Care Practice Collide

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Obesity: Where Pathophysiology and NP Primary Care Practice Collide

Recorded for 2025 National Conference

Credit(s):

1.68 Contact Hour(s) of CE; 0.84 of which may be applied towards Pharmacology

Program Number:

25057203

Original Program Date:

June 27, 2025

Duration:

1 hour 41 minutes

Access:

Available until July 15, 2026

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Description
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Dates and Locations

(117)

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Category: 2025 National Conference, Cardiometabolic, Cert Exam Domain - Evaluation ... (show more)

Category: 2025 National Conference, Cardiometabolic, Cert Exam Domain - Evaluation, Cert Exam Domain - Planning, Diabetes Mellitus, Family, Genetics/Genomics, Outpatient, Recent Additions (show less)

Activity Duration

Content Expires:

July 15, 2026 (11:55 p.m. CT)
CE for this activity will not be available after this date.

This CE activity was recorded for the 2025 AANP National Conference.

This activity includes closed captioning.

Delivery Note: The content for this activity was previously presented during the 2025 AANP National Conference. If you already completed the content of this activity while attending the live or virtual conference, you should not complete this content a second time. Learners should only complete ONE delivery-method to earn credit. Completing multiple delivery options for the same activity is considered duplicate credit for the same content and will not be accepted by regulatory bodies.

Overview
This presentation reviews and explores the intricate pathophysiology of obesity, highlighting genetic, hormonal, and environmental factors that contribute to its development. Central to obesity's pathogenesis is dysregulation in energy balance, involving key hormones such as leptin and insulin, along with the endocrine properties of adipose tissue. For the NP practicing in primary care, practical applications in managing obesity will be critically analyzed, including lifestyle interventions, behavioral modification and support, pharmacotherapy, and surgical options. Lifestyle modifications, particularly diet and physical activity, remain foundational, but their long-term efficacy is often limited by physiological adaptations. Pharmacological treatments offer adjunctive benefits, targeting appetite regulation and metabolic pathways. Metabolic and bariatric surgery provides significant and sustained weight loss for severe obesity, though it is associated with potential complications. This intersection of pathophysiological insights and practical treatment strategies underscores the need for a multifaceted approach to obesity management in the primary care setting. Personalized medicine, integrating genetic, epigenetic, and environmental data, holds promise for optimizing therapeutic outcomes. Barriers to obesity management in primary care will be discussed. Case studies will link manifestations of disease pathology with clinical assessment and evidence-based treatment options to reduce obesity's disease burden and improve health.

Objectives

Describe the basic pathophysiology of the chronic disease of obesity with contributing factors to the development of obesity.
Review current FDA approved medications for the treatment of obesity.
Discuss management strategies, including pharmacotherapy, in the treatment of obesity in primary care.

Speakers
Jennifer Kucera, MSN, APRN, FNP-C, FOMA
Nancy T. Browne, MS, PPCNP-BC, FOMA, FAANP, FAAN

Disclosure
This program was planned in accordance with AANP CE Standards and Policies.

The speakers have the following disclosures:

The presenters have nothing to disclose.

Disclaimer
Individuals who have contributed to the CE Center (content originally from the 2025 AANP National Conference) were carefully selected for their knowledge and experience in the subject area under review. This presentation is informational only and may contain opinions of the authors from their personal experience that do not necessarily express the opinions of the American Association of Nurse Practitioners (AANP). The activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Clinical practice is a constantly changing process and new information becomes available every day. Neither AANP nor the contributing individuals can warrant that the material will continue to be accurate, nor do they warrant that the material is completely free of errors upon publication. Attendees and participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.

CE Credit Instructions

Read this activity description, including objectives and disclosures.
Complete all educational content:
- OnDemand Presentations: Click the Play button to watch the activity video lecture. To get full credit for the learning activity portion, you must watch all of the video content.
- Click on the Additional Resources button to review all additional materials provided (handouts and any other downloadable resources).
After completing all educational content, go to the Next Steps button:
- Submit the activity evaluation to receive full AANP CE/Rx credit.
- Click on the Get Certificate button. At the top of the certificate screen, use the provided dropdown menu and select AANP Certificate of Completion.
  - A copy of your certificate of completion will display on the screen for you to print or save. A copy of the certificate will also be emailed to you.
  - A copy of the certificate will be automatically added to your AANP CE Tracker.

Additional Information
For questions or more information concerning this online CE activity, please visit the AANP Help Center to find answers to frequently asked questions and request assistance.

1.68 Contact Hour(s) of CE,
0.84 of which may be applied towards Pharmacology